Origin of Syphilis

The origin of syphilis.

In an opening address on the above subject to the Osler Club, London, on April 22, 1958, Prof. J. F. D. Shrewsbury advanced the (to me) novel suggestion that syphilis in its present form, which undoubtedly caused great alarm to health authorities in Europe in the late 90s of the 15th century, was due to the mutation about 1493 of a treponeme which had hitherto caused a milder form of treponemat...

Experimental Syphilis of Oriental Origin: Clinical Reaction in the Rabbit

Two oriental strains of T. pallidum of Chinese origin were compared with two well known occidental strains, the Nichols and the Zinsser-Hopkins, on the basis of the clinical reaction to infection in the rabbit. Four experiments were carried out, two each in Peiping and New York. Animals from American and Chinese sources were represented in each experiment. The results obtained showed that the r...

Congenital Syphilis

Two cases of congenital syphilis was presented and few aspect of the disease and its treatment was discussed.

Syphilis and Pseudo-Syphilis

On the Origin of Syphilis and Contemporary Views of Disease Dynamics

Despite effective treatment availability for nearly a century, syphilis remains a global public health problem with significant social and economic impact. Over 500 years after the first reports of this sexually transmitted infection, questions remain regarding its origins, relationship to other infectious agents and effective control measures. Studies addressing origins of syphilis and non-syp...